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| 1999 Grants |
| Investigator |
Institution |
Project Title |
Grant Duration |
Amt Granted |
| David Badesch,
M.D. |
University of
Colorado Health Sciences Center
Denver, Colo. |
Relative Arginine
Deficiency in Pulmonary Hypertension Secondary to the
Scleroderma Spectrum of Diseases |
Two Years |
$100,000 |
| Constantin Bona,
M.D., P.hD. |
Mount Sinai School
of Medicine
New York, N.Y. |
Involvement of
partially duplicated fibrillin-1 gene in the development
of TSK syndrome |
One Year |
$50,000 |
| Carol Feghali,
Ph.D. |
University of
Pittsburgh
Pittsburgh, Penn. |
Analysis of Twins
with Systemic Sclerosis |
Two Years |
$100,000 |
| Humphrey Gardner,
M.D. |
The Scripps Research
Institute
La Jolla, Calif. |
Integrin Regulation
of Metalloproteases in the Dermis |
Two Years |
$92,351 |
| Gloria Higgins,
M.D., Ph.D. |
University of
Tennessee
Memphis, Tenn. |
Intracellular
IL-1ra and precursor IL-1a regulation fibroblast matrix |
Two Years |
$50,000 |
| Stanley Hoffman,
Ph.D. |
Medical University
of South Carolina
Charleston, S.C. |
Curcumin sensitivity
and altered PKC in scleroderma |
One Year |
$50,000 |
| Frank Jirik,
M.D. |
University of
British Columbia
Vancouver, B.C. |
The Role of Interleukin-4
in the Tight Skin Model of Dermal Fibrosis: A Genetic
Analysis |
Two Years |
$99,932 |
| Richard Kew,
Ph.D. |
SUNY at Stony
Brook
Stony Brook, N.Y. |
Mast Cells Induce
Myofibroblast Formation: Implications in Scleroderma |
Two Years |
$100,000 |
| Anna Ludwicka,
Ph.D. |
Medical University
of South Carolina
Charleston, S.C. |
The role of thrombin
in induction of myofibroblast phenotype in scleroderma
lung disease |
Two Years |
$100,000 |
| Arnold Postlethwaite,
M.D. |
University of
Tennessee
Memphis, Tenn. |
Mapping of Epitopes
on a1 Type I Collagen Reactive with Scleroderma T Cells |
One Year |
$50,000 |
| Biagio Saitta,
Ph.D. |
Thomas Jefferson
University
Philadelphia, Penn. |
Regulation of
type I and type VI collagen genes in scleroderma and normal
human fibroblasts: role of the B-myb transcription factor |
Two Years |
$100,000 |
| Lynn Sakai, Ph.D. |
Shriners Hospital
for Children
Portland, Ore. |
Does fragmentation
of fibrillin microfibrils contribute to scleroderma? |
Two Years |
$100,000 |
| Robert Stern,
M.D. |
University of
California, San Francisco
San Francisco, Calif. |
Aberrations in
Hyaluronan Metabolism in Scleroderma |
Two Years |
$100,000 |
| David Strehlow,
Ph.D. |
Boston University
School of Medicine
Boston, Mass. |
Large Array Expression
Fingerprinting of Scleroderma Fibroblasts |
Two Years |
$100,000 |
| Paul Utz, M.D. |
Brigham and Women's
Hospital
Boston, Mass. |
Posttranslational
modifications of proteins associated with the U3-snoRNP
following environmental stress |
One Year |
$50,000 |
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Total Granted 1999: |
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$1,242,283 |
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| All
grants funded by the Scleroderma Foundation. |
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