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2010 Scleroderma Researchers

1991 Grants
Investigator Institution Project Title Grant Duration Amt Granted
Stephen Clark, M.D. * VA Medical Center
Newington, Conn.
Genetic and molecular analysis of the tight skin locus in the mouse One Year $43,208
Benoit de Crombrugghe, M.D. ** University of Texas
Houston, Texas
Molecular mechanisms of Type I & III collagen synthesis in scleroderma fibroblasts One Year $43,972
William Earnshaw, Ph.D. * Johns Hopkins University
Baltimore, Md.
Development of improved assays for the detection of anti-centromere antibodies One Year $22,000
Robert Garver, Jr., M.D. * University of Alabama
Birmingham, Ala.
Growth factor expression protein production on the lower respiratory tract of individuals with scleroderma One Year $44,000
Barry Gruber, M.D. ** SUNY at Stony Brook
Albany, N.Y.
Role of mast cells in tryptase in the pathogenesis of scleroderma (renewal) One Year $40,973
Mary Jones, M.D. ** University of Iowa
Iowa City, Iowa
Investigation of immune dysregulation in a murine model of eosinophilia-myalgia syndrome One Year $44,000
G. J. Laurent, Ph.D. * National Heart & Lung Institute
London, England
Localization of transforming growth factor B in the lungs of patients with systemic sclerosis and assessment of its role in the regulation of collagen gene expression One Year $43,732
Gerd Maul, Ph.D. * Wistar Institute
Philadelphia, Penn.
Fibroblast and endothelial cells in pathogenesis of scleroderma One Year $44,000
James Norris, Ph.D. * Medical University of South Carolina
Charleston, S.C.
Analysis of the development of TSK phenotype and its linkage to chromosome One Year $43,560
Noelynn Oliver, Ph.D. ** Tufts University
Boston, Mass.
Fibronectin gene expression in abnormal wound healing One Year $44,000
Daniel Pennington, M.D.* North California Institute for Research and Education
San Francisco, Calif.
Purification of a mast cell-derived growth factor for fibroblasts One Year $43,845
Ignacio Sanz, M.D. * University of Texas
San Antonio, Tx.
Genetic basis of scleroderma specific autoantibodies One Year $44,000
Richard Silver, M.D. * Medical University of South Carolina
Charleston, S.C.
Cytokines and fibrosis in scleroderma lung disease One Year $44,000
Ethylin Wang Jabs, M.D. * Johns Hopkins University
Baltimore, Md.
Molecular mechanisms of antro-centromere antibody mediated chromosomal abnormalities in systemic sclerosis One Year $44,000
Barbara White Needleman, M.D. ** University of Maryland
Baltimore, Md.
Diversity of V (delta) 1/C (gamma) 2 bearing T cells in patients with scleroderma One Year $44,000
Frederick Wigley, M.D. * Johns Hopkins University
Baltimore, Md.
Assessment of peripheral circulation in patients with systemic sclerosis using continuous ambulatory skin temperature monitoring (CAST) One Year $34,166
Martin Zamora, M.D. * University of Colorado
Denver, Colo.
Cause and consequence of endothelial dysfunction in progressive systemic sclerosis: a potential contributor to vascular obstruction One Year $44,000
    Total Granted 1991:   $711,456

* Grant collaboratively funded by the Scleroderma Federation, the Scleroderma Research Fund, and the United Scleroderma Foundation.
** Grant funded solely by the Scleroderma Federation.

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