| 1991 Grants |
| Investigator |
Institution |
Project Title |
Grant Duration |
Amt Granted |
| Stephen Clark,
M.D. * |
VA Medical Center
Newington, Conn. |
Genetic and molecular
analysis of the tight skin locus in the mouse |
One Year |
$43,208 |
| Benoit de Crombrugghe,
M.D. ** |
University of
Texas
Houston, Texas |
Molecular mechanisms
of Type I & III collagen synthesis in scleroderma
fibroblasts |
One Year |
$43,972 |
| William Earnshaw,
Ph.D. * |
Johns Hopkins
University
Baltimore, Md. |
Development of
improved assays for the detection of anti-centromere antibodies |
One Year |
$22,000 |
| Robert Garver,
Jr., M.D. * |
University of
Alabama
Birmingham, Ala. |
Growth factor
expression protein production on the lower respiratory
tract of individuals with scleroderma |
One Year |
$44,000 |
| Barry Gruber,
M.D. ** |
SUNY at Stony
Brook
Albany, N.Y. |
Role of mast
cells in tryptase in the pathogenesis of scleroderma (renewal) |
One Year |
$40,973 |
| Mary Jones, M.D.
** |
University of
Iowa
Iowa City, Iowa |
Investigation
of immune dysregulation in a murine model of eosinophilia-myalgia
syndrome |
One Year |
$44,000 |
| G. J. Laurent,
Ph.D. * |
National Heart
& Lung Institute
London, England |
Localization
of transforming growth factor B in the lungs of patients
with systemic sclerosis and assessment of its role in
the regulation of collagen gene expression |
One Year |
$43,732 |
| Gerd Maul, Ph.D.
* |
Wistar Institute
Philadelphia, Penn. |
Fibroblast and
endothelial cells in pathogenesis of scleroderma |
One Year |
$44,000 |
| James Norris,
Ph.D. * |
Medical University
of South Carolina
Charleston, S.C. |
Analysis of the
development of TSK phenotype and its linkage to chromosome |
One Year |
$43,560 |
| Noelynn Oliver,
Ph.D. ** |
Tufts University
Boston, Mass. |
Fibronectin gene
expression in abnormal wound healing |
One Year |
$44,000 |
| Daniel Pennington,
M.D.* |
North California
Institute for Research and Education
San Francisco, Calif. |
Purification
of a mast cell-derived growth factor for fibroblasts |
One Year |
$43,845 |
| Ignacio Sanz,
M.D. * |
University of
Texas
San Antonio, Tx. |
Genetic basis
of scleroderma specific autoantibodies |
One Year |
$44,000 |
| Richard Silver,
M.D. * |
Medical University
of South Carolina
Charleston, S.C. |
Cytokines and
fibrosis in scleroderma lung disease |
One Year |
$44,000 |
| Ethylin Wang
Jabs, M.D. * |
Johns Hopkins
University
Baltimore, Md. |
Molecular mechanisms
of antro-centromere antibody mediated chromosomal abnormalities
in systemic sclerosis |
One Year |
$44,000 |
| Barbara White
Needleman, M.D. ** |
University of
Maryland
Baltimore, Md. |
Diversity of
V (delta) 1/C (gamma) 2 bearing T cells in patients with
scleroderma |
One Year |
$44,000 |
| Frederick Wigley, M.D. * |
Johns Hopkins University
Baltimore, Md. |
Assessment of peripheral
circulation in patients with systemic sclerosis using
continuous ambulatory skin temperature monitoring (CAST) |
One Year |
$34,166 |
| Martin Zamora, M.D. * |
University of Colorado
Denver, Colo. |
Cause and consequence of
endothelial dysfunction in progressive systemic sclerosis:
a potential contributor to vascular obstruction |
One Year |
$44,000 |
| |
|
Total Granted 1991: |
|
$711,456 |