About Murali Chakinala, M.D.

Murali Chakinala, M.D. is Associate Professor of Medicine, Pulmonary & Critical Care Medicine at Washington University School of Medicine. His research interests include therapeutics and non-invasive monitoring in pulmonary hypertension and respiratory viruses in lung transplantation.

Dr. Chakinala did his residency at University of Texas Southwestern at Dallas, Texas. He is a Fellow at Washington University School of Medicine in St. Louis, Missouri.

Honors and Awards

• 1993 Alpha Omega Alpha - Vanderbilt University
• 2006 RM Senior Oustanding Attending Physician

Research

Dr. Chakinala's research is patient-oriented and primarily involves patients with pulmonary vascular disorders.

He is (local) principal investigator for several multi-centered clinical investigations for the treatment of pulmonary arterial hypertension. He is also studying non-invasive techniques for the longitudinal assessment of patients with pulmonary arterial hypertension, including application of a bed-side Doppler machine for rapid flow (cardiac output) assessment.

He is nterested in the application of multi-planar computed tomography (CT) for the initial diagnosis and follow-up of pulmonary arterio-venous malformations in patients with hereditary hemorrhagic telangiectasia.

Publications

His most recent publications include:

1. Daud SA, Yusen RD, Meyers BF, Chakinala MM, Walter MJ, Aloush AA, Patterson GA, Trulock EP, Hachem RR. "Impact of Immediate Primary Lung Allograft Dysfunction on Bronchiolitis Obliterans Syndrome." Am J Respir Crit Care Med. 2007; 175: 507-513.

2. Mikols, C.L., Yan, L., Norris, J.Y., Russell, T.D., Khalifah, A.P., Hachem, R.R., Chakinala, M.M., Yusen, R.D., Castro, M., Kuo, E., Patterson, G.A., Mohanakumar, T., Trulock, E.P., Walter, M.J. IL-12 p80 "Is an Innate Epithelial Cell Effector That Mediates Chronic Allograft Dysfunction." Am J Respir Crit Care Med. 2006. 174:461-470.